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Mice transgenic for the gene encoding murine lymphocyte function-associated antigen 3 (mLA3) express this molecule on their T cells and are resistant to ovalbumin-induced experimental allergic encephalomyelitis. We have investigated whether T cells from transgenic mice could be stimulated in vitro to express mLA3 and elicit an immune response in normal mice. Four plasmid DNA constructs were designed to express different murine mLA3 (mLA3-1, mLA3-2, mLA3-3, and mLA3-4). After direct inoculation into mice, plasmid DNA expressing mLA3-1, 2, 3, or 4 induced T-cell-mediated immunity to ovalbumin in a gene dose-dependent fashion. Maximal T-cell-mediated immunity to ovalbumin was induced when mice received plasmid DNA expressing mLA3-2 or mLA3-4. The results demonstrate that the transgene coding for murine mLA3 can be expressed in T cells in a gene dose-dependent manner and that immunity to an unrelated antigen can be induced by such expression.Q:
Is there any way to prevent a `blocked` anf `application_close` event from occurring when using a service worker?
A lot of people make a mistake when installing a service worker. They register a service worker using the Install event. That event fires when a user opens the app from within the app. This is great, because we get to listen to the Install event whenever a user opens the app.
Unfortunately, there are a lot of other events. Not only does this service worker use the Install event to notify of the install (which is good), but it also uses the following Event Listeners:
file
network
blocked
application_close
The problem is that these events fire when a user goes to a different page, which doesn’t mean the user actually opened the app. It’s just that the user loaded a different page.
The expected behavior is that these events would only fire when someone is actually opening the app.
Is there any way I could prevent these events from
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